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Universal reaction: CH25H


Descriptive name:

Cholesterol 25-hydroxylase

Reaction:

h_r + nadph_r + o2_r + chsterol_r ⇌ h2o_r + nadp_r + xol25oh_r

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
h2o_r
H2O H2O
-1.0
h_r
H+
1.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_r
O2 O2
-1.0
chsterol_r
Chsterol c
1.0
xol25oh_r
25-Hydroxycholesterol

CH25H in BiGG models:

Organism
Model
Cricetulus griseus
iCHOv1
Mus musculus
iMM1415
Homo sapiens
RECON1
Homo sapiens
Recon3D

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External database links

  • RHEA: 46132, 46133, 46134, 46135
  • MetaNetX (MNX) Equation: MNXR96660
  • Reactome Reaction: R-BTA-191983, R-CEL-191983, R-CFA-191983, R-DRE-191983, R-GGA-191983, R-HSA-191983, R-MMU-191983, R-RNO-191983, R-SCE-191983, R-SSC-191983, R-TGU-191983, R-XTR-191983

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    CH25H

Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049


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