Universal reaction: FPGS

Descriptive name:

Folylpolyglutamate synthetase

Reaction:

4.0 atp_c + 4.0 glu__L_c + thf_c ⇌ 4.0 adp_c + 4.0 h_c + 4.0 pi_c + 5thf_c

Metabolites:

Stoichiometry
BiGG ID
Name
4.0
adp_c
ADP C10H12N5O10P2
-4.0
atp_c
ATP C10H12N5O13P3
-4.0
glu__L_c
L-Glutamate
4.0
h_c
H+
4.0
pi_c
Phosphate
-1.0
thf_c
5,6,7,8-Tetrahydrofolate
1.0
5thf_c
Pentaglutamyl folate (THF)

FPGS in BiGG models:

Organism
Model
Plasmodium berghei
iAM_Pb448
Plasmodium cynomolgi strain B
iAM_Pc455
Plasmodium falciparum 3D7
iAM_Pf480
Plasmodium knowlesi strain H
iAM_Pk459
Plasmodium vivax Sal-1
iAM_Pv461
Cricetulus griseus
iCHOv1
Cricetulus griseus
iCHOv1_DG44
Mus musculus
iMM1415
Homo sapiens
RECON1

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Old identifiers

    FPGS