Universal reaction: HMGCOAR

Descriptive name:

Hydroxymethylglutaryl CoA reductase

Reaction:

coa_c + 2.0 nadp_c + mev__R_c ⇌ 2.0 h_c + 2.0 nadph_c + hmgcoa_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
coa_c
Coenzyme A
2.0
h_c
H+
-2.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
2.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
1.0
hmgcoa_c
Hydroxymethylglutaryl CoA C27H39N7O20P3S
-1.0
mev__R_c
R Mevalonate C6H11O4

HMGCOAR in BiGG models:

Organism
Model
Methanosarcina barkeri str. Fusaro
iAF692
Cricetulus griseus
iCHOv1
Cricetulus griseus
iCHOv1_DG44
Phaeodactylum tricornutum CCAP 1055/1
iLB1027_lipid
Saccharomyces cerevisiae S288C
iMM904
Saccharomyces cerevisiae S288C
iND750
Lactococcus lactis subsp. cremoris MG1363
iNF517
Staphylococcus aureus subsp. aureus N315
iSB619
Staphylococcus aureus subsp. aureus USA300_TCH1516
iYS854
Homo sapiens
Recon3D

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Old identifiers

    HMGCOAR, HMGCOARc, HMGCOAR_c, HMGCOARi, r0488