Universal reaction: HPPK

Descriptive name:

2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase

Reaction:

atp_c + 2ahhmp_c ⇌ amp_c + h_c + 2ahhmd_c

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
amp_c
AMP C10H12N5O7P
-1.0
atp_c
ATP C10H12N5O13P3
1.0
h_c
H+
-1.0
2ahhmp_c
2 Amino 4 hydroxy 6 hydroxymethyl 7 8 dihydropteridine C7H9N5O2
1.0
2ahhmd_c
2 Amino 4 hydroxy 6 hydroxymethyl 7 8 dihydropteridine diphosphate C7H8N5O8P2

HPPK in BiGG models:

Organism
Model
Plasmodium berghei
iAM_Pb448
Plasmodium cynomolgi strain B
iAM_Pc455
Plasmodium falciparum 3D7
iAM_Pf480
Plasmodium knowlesi strain H
iAM_Pk459
Plasmodium vivax Sal-1
iAM_Pv461
Acinetobacter baumannii AYE
iCN718
Mycobacterium tuberculosis H37Rv
iEK1008
Clostridium ljungdahlii DSM 13528
iHN637
Helicobacter pylori 26695
iIT341
Synechococcus elongatus PCC 7942
iJB785
Pseudomonas putida KT2440
iJN1463
Synechocystis sp. PCC 6803
iJN678
Pseudomonas putida KT2440
iJN746
Thermotoga maritima MSB8
iLJ478
Lactococcus lactis subsp. cremoris MG1363
iNF517
Mycobacterium tuberculosis H37Rv
iNJ661
Synechocystis sp. PCC 6803
iSynCJ816
Bacillus subtilis subsp. subtilis str. 168
iYO844

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Old identifiers

    HPPK