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Universal reaction: OIVD1m


Descriptive name:

2-oxoisovalerate dehydrogenase (acylating; 4-methyl-2-oxopentaoate), mitochondrial

Reaction:

4mop_m + coa_m + nad_m ⇌ co2_m + nadh_m + ivcoa_m

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
4mop_m
4-Methyl-2-oxopentanoate
1.0
co2_m
CO2 CO2
-1.0
coa_m
Coenzyme A
-1.0
nad_m
Nicotinamide adenine dinucleotide
1.0
nadh_m
Nicotinamide adenine dinucleotide - reduced
1.0
ivcoa_m
Isovaleryl-CoA

OIVD1m in BiGG models:

Organism
Model
Plasmodium berghei
iAM_Pb448
Plasmodium cynomolgi strain B
iAM_Pc455
Plasmodium falciparum 3D7
iAM_Pf480
Plasmodium knowlesi strain H
iAM_Pk459
Plasmodium vivax Sal-1
iAM_Pv461
Homo sapiens
iAT_PLT_636
Cricetulus griseus
iCHOv1
Phaeodactylum tricornutum CCAP 1055/1
iLB1027_lipid
Mus musculus
iMM1415
Homo sapiens
RECON1
Homo sapiens
Recon3D

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External database links

  • RHEA: 25177, 25178, 25179, 25180
  • KEGG Reaction: R01651
  • MetaNetX (MNX) Equation: MNXR102172
  • BioCyc: META:2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN
  • EC Number: 1.2.1, 1.2.1.25
  • SEED Reaction: rxn01207

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    BCKDHL_m, OIVD1m, OIVD1mr

Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049


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