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Universal reaction: OPAH


Descriptive name:

5-Oxoproline amidohydrolase (ATP-hydrolysing) (ir)

Reaction:

atp_c + 2.0 h2o_c + 5oxpro_c ⇌ adp_c + glu__L_c + h_c + pi_c

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
adp_c
ADP C10H12N5O10P2
-1.0
atp_c
ATP C10H12N5O13P3
1.0
glu__L_c
L-Glutamate
1.0
h_c
H+
-2.0
h2o_c
H2O H2O
1.0
pi_c
Phosphate
-1.0
5oxpro_c
5-Oxoproline

OPAH in BiGG models:

Organism
Model
Homo sapiens
iAB_RBC_283
Methanosarcina barkeri str. Fusaro
iAF692
Homo sapiens
iAT_PLT_636
Cricetulus griseus
iCHOv1
Mycobacterium tuberculosis H37Rv
iEK1008
Trypanosoma cruzi Dm28c
iIS312
Trypanosoma cruzi Dm28c
iIS312_Amastigote
Trypanosoma cruzi Dm28c
iIS312_Epimastigote
Trypanosoma cruzi Dm28c
iIS312_Trypomastigote
Synechococcus elongatus PCC 7942
iJB785
Pseudomonas putida KT2440
iJN1463
Mus musculus
iMM1415
Mycobacterium tuberculosis H37Rv
iNJ661
Homo sapiens
RECON1
Homo sapiens
Recon3D

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External database links

  • RHEA: 10348, 10349, 10350, 10351
  • KEGG Reaction: R00251
  • BioCyc: META:5-OXOPROLINASE-ATP-HYDROLYSING-RXN
  • Reactome Reaction: R-ATH-1247935, R-BTA-1247935, R-CEL-1247935, R-CFA-1247935, R-DDI-1247935, R-DME-1247935, R-DRE-1247935, R-HSA-1247935, R-MMU-1247935, R-OSA-1247935, R-RNO-1247935, R-SCE-1247935, R-SPO-1247935, R-SSC-1247935, R-XTR-1247935
  • EC Number: 3.5.2.9
  • SEED Reaction: rxn00186
  • MetaNetX (MNX) Equation: MNXR138674

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    5OPROS, OPAH, OPAHir

Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049


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