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Universal reaction: PPBNGD


Descriptive name:

Porphobilinogen deaminase

Reaction:

h2o_h + 4.0 ppbng_h ⇌ hmbil_h + 4.0 nh4_h

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h2o_h
H2O H2O
1.0
hmbil_h
Hydroxymethylbilane
4.0
nh4_h
Ammonium
-4.0
ppbng_h
Porphobilinogen

PPBNGD in BiGG models:

Organism
Model
Plasmodium berghei
iAM_Pb448
Plasmodium cynomolgi strain B
iAM_Pc455
Plasmodium falciparum 3D7
iAM_Pf480
Plasmodium knowlesi strain H
iAM_Pk459
Plasmodium vivax Sal-1
iAM_Pv461
Phaeodactylum tricornutum CCAP 1055/1
iLB1027_lipid
Chlamydomonas reinhardtii
iRC1080

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External database links

  • RHEA: 13185, 13186, 13187, 13188
  • KEGG Reaction: R00084
  • BioCyc: META:OHMETHYLBILANESYN-RXN
  • Reactome Reaction: R-ATH-189406, R-BTA-189406, R-CFA-189406, R-DDI-189406, R-DME-189406, R-DRE-189406, R-GGA-189406, R-GGA-421439, R-HSA-189406, R-MMU-189406, R-OSA-189406, R-PFA-189406, R-RNO-189406, R-SCE-189406, R-SPO-189406, R-SSC-189406, R-TGU-189406, R-XTR-189406
  • EC Number: 2.5.1.61, 4.3.1.8
  • SEED Reaction: rxn00060
  • MetaNetX (MNX) Equation: MNXR100658

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    HMBSc, PPBNGD, PPBNGD_h

Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049


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