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Universal reaction: PPNCL3


Descriptive name:

4'-Phosphopantothenate:L-cysteine ligase

Reaction:

4ppan_c + atp_c + cys__L_c ⇌ 4ppcys_c + amp_c + h_c + ppi_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
4ppan_c
D-4'-Phosphopantothenate
1.0
4ppcys_c
N-((R)-4-Phosphopantothenoyl)-L-cysteine
1.0
amp_c
AMP C10H12N5O7P
-1.0
atp_c
ATP C10H12N5O13P3
-1.0
cys__L_c
L-Cysteine
1.0
h_c
H+
1.0
ppi_c
Diphosphate

PPNCL3 in BiGG models:

Organism
Model
Cricetulus griseus
iCHOv1
Clostridioides difficile 630
iCN900
Mycobacterium tuberculosis H37Rv
iEK1008
Synechococcus elongatus PCC 7942
iJB785
Mus musculus
iMM1415
Mycobacterium tuberculosis H37Rv
iNJ661
Chlamydomonas reinhardtii
iRC1080
Synechocystis sp. PCC 6803
iSynCJ816
Homo sapiens
RECON1
Homo sapiens
Recon3D

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External database links

  • RHEA: 25156, 25157, 25158, 25159
  • KEGG Reaction: R04230
  • BioCyc: META:RXN66-555
  • Reactome Reaction: R-ATH-196753, R-BTA-196753, R-CEL-196753, R-CFA-196753, R-DDI-196753, R-DME-196753, R-DRE-196753, R-GGA-196753, R-HSA-196753, R-MMU-196753, R-OSA-196753, R-PFA-196753, R-RNO-196753, R-SCE-196753, R-SPO-196753, R-SSC-196753, R-TGU-196753, R-XTR-196753
  • EC Number: 6.3.2, 6.3.2.5
  • SEED Reaction: rxn12512
  • MetaNetX (MNX) Equation: MNXR103120

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    PPCL, PPNCL1, PPNCL3

Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049


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