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Universal reaction: SPR


Descriptive name:

Sepiapterin reductase

Reaction:

2.0 h_c + 2.0 nadph_c + 6pthp_c ⇌ 2.0 nadp_c + thbpt_c

Metabolites:

Stoichiometry
BiGG ID
Name
-2.0
h_c
H+
2.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
-2.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
6pthp_c
6-Pyruvoyl-5,6,7,8-tetrahydropterin
1.0
thbpt_c
Tetrahydrobiopterin

SPR in BiGG models:

Organism
Model
Plasmodium berghei
iAM_Pb448
Plasmodium cynomolgi strain B
iAM_Pc455
Plasmodium falciparum 3D7
iAM_Pf480
Plasmodium knowlesi strain H
iAM_Pk459
Plasmodium vivax Sal-1
iAM_Pv461
Cricetulus griseus
iCHOv1
Synechococcus elongatus PCC 7942
iJB785
Phaeodactylum tricornutum CCAP 1055/1
iLB1027_lipid
Mus musculus
iMM1415
Homo sapiens
RECON1
Homo sapiens
Recon3D

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External database links

  • RHEA: 24738, 24739, 24740, 24741, 32627, 32628, 32629, 32630
  • KEGG Reaction: R08208
  • BioCyc: META:RXN-8853
  • Reactome Reaction: R-BTA-1475414, R-CFA-1475414, R-DDI-1475414, R-DME-1475414, R-DRE-1475414, R-GGA-1475414, R-HSA-1475414, R-MMU-1475414, R-RNO-1475414, R-SCE-1475414, R-SSC-1475414, R-XTR-1475414
  • EC Number: 1.1.1.153
  • SEED Reaction: rxn11742
  • MetaNetX (MNX) Equation: MNXR138834

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    SPR, SR_c

Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049


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