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Reaction: GTHOm


Descriptive name:

Glutathione oxidoreductase

Model:

Recon3D

Reaction:

gthox_m + h_m + nadph_m → 2.0 gthrd_m + nadp_m

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
gthox_m
Oxidized glutathione
2.0
gthrd_m
Reduced glutathione
-1.0
h_m
H+
1.0
nadp_m
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_m
Nicotinamide adenine dinucleotide phosphate - reduced

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Glutamate metabolism

Gene Reaction Rule:

2936_AT1

Genes:

2936_AT1 (GSR)


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Universal reaction ?

  • GTHOm

External database links

  • RHEA: 11740, 11741, 11742, 11743
  • KEGG Reaction: R00115
  • BioCyc: META:GLUTATHIONE-REDUCT-NADPH-RXN
  • Reactome Reaction: R-ATH-3323079, R-ATH-71682, R-BTA-3323079, R-BTA-71682, R-CEL-3323079, R-CEL-71682, R-CFA-3323079, R-CFA-71682, R-DDI-3323079, R-DDI-71682, R-DRE-3323079, R-DRE-71682, R-GGA-3323079, R-GGA-71682, R-HSA-3323079, R-HSA-71682, R-MMU-3323079, R-MMU-71682, R-OSA-3323079, R-OSA-71682, R-PFA-3323079, R-PFA-71682, R-RNO-3323079, R-RNO-71682, R-SCE-3323079, R-SCE-71682, R-SPO-3323079, R-SPO-71682, R-SSC-3323079, R-SSC-71682, R-TGU-3323079, R-TGU-71682, R-XTR-3323079, R-XTR-71682
  • EC Number: 1.8.1.7
  • SEED Reaction: rxn00086
  • MetaNetX (MNX) Equation: MNXR100098

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    GTHOm

GTHOm in other models

  • iAT_PLT_636
  • iCHOv1
  • iCHOv1_DG44
  • iLB1027_lipid
  • iMM1415
  • iMM904
  • iRC1080
  • RECON1
  • Recon3D

Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049


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